Norfloxacin
Brand names,
Norfloxacin
Analogs
Norfloxacin
Brand Names Mixture
Norfloxacin
Chemical_Formula
C16H18FN3O3
Norfloxacin
RX_link
http://www.rxlist.com/cgi/generic3/norfloxacin.htm
Norfloxacin
fda sheet
Norfloxacin
msds (material safety sheet)
Norfloxacin
Synthesis Reference
No information avaliable
Norfloxacin
Molecular Weight
319.331 g/mol
Norfloxacin
Melting Point
227-228 oC
Norfloxacin
H2O Solubility
1.78E+005 mg/L
Norfloxacin
State
Solid
Norfloxacin
LogP
1.176
Norfloxacin
Dosage Forms
Tablet; Solution
Norfloxacin
Indication
For the treatment of urinary tract infection
Norfloxacin
Pharmacology
Norfloxacin is a quinolone/fluoroquinolone antibiotic. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase, which allows the untwisting required to replicate one DNA double helix into two. Notably the drug has 100 times higher affinity for bacterial DNA gyrase than for mammalian.
Norfloxacin
Absorption
rapid
Norfloxacin
side effects and Toxicity
No information avaliable
Norfloxacin
Patient Information
No information avaliable
Norfloxacin
Organisms Affected
Enteric bacteria and other eubacteria