Norfloxacin (JP14/USP)
Brand names,
Norfloxacin (JP14/USP)
Analogs
Norfloxacin (JP14/USP)
Brand Names Mixture
Norfloxacin (JP14/USP)
Chemical_Formula
C16H18FN3O3
Norfloxacin (JP14/USP)
RX_link
http://www.rxlist.com/cgi/generic3/norfloxacin.htm
Norfloxacin (JP14/USP)
fda sheet
Norfloxacin (JP14/USP)
msds (material safety sheet)
Norfloxacin (JP14/USP)
Synthesis Reference
No information avaliable
Norfloxacin (JP14/USP)
Molecular Weight
319.331 g/mol
Norfloxacin (JP14/USP)
Melting Point
227-228 oC
Norfloxacin (JP14/USP)
H2O Solubility
1.78E+005 mg/L
Norfloxacin (JP14/USP)
State
Solid
Norfloxacin (JP14/USP)
LogP
1.176
Norfloxacin (JP14/USP)
Dosage Forms
Tablet; Solution
Norfloxacin (JP14/USP)
Indication
For the treatment of urinary tract infection
Norfloxacin (JP14/USP)
Pharmacology
Norfloxacin is a quinolone/fluoroquinolone antibiotic. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase, which allows the untwisting required to replicate one DNA double helix into two. Notably the drug has 100 times higher affinity for bacterial DNA gyrase than for mammalian.
Norfloxacin (JP14/USP)
Absorption
rapid
Norfloxacin (JP14/USP)
side effects and Toxicity
No information avaliable
Norfloxacin (JP14/USP)
Patient Information
No information avaliable
Norfloxacin (JP14/USP)
Organisms Affected
Enteric bacteria and other eubacteria