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Nevirapine Brand names, Nevirapine Analogs

Nevirapine Brand Names Mixture

  • No information avaliable

Nevirapine Chemical_Formula

C15H14N4O

Nevirapine RX_link

http://www.rxlist.com/cgi/generic2/nevira.htm

Nevirapine fda sheet

Nevirapine FDA

Nevirapine msds (material safety sheet)

Nevirapine MSDS

Nevirapine Synthesis Reference

Hargrave, Karl D., et al.; J.Med.Chem.; 34; 7;2231-2241(1991).

Nevirapine Molecular Weight

266.298 g/mol

Nevirapine Melting Point

196.06

Nevirapine H2O Solubility

0.7046 mg/L

Nevirapine State

Solid

Nevirapine LogP

1.725

Nevirapine Dosage Forms

Tablets; Oral suspension

Nevirapine Indication

For use in combination with other antiretroviral drugs in the ongoing treatment of HIV-1 infection.

Nevirapine Pharmacology

Nevirapine is a non-nucleoside reverse transcriptase inhibitor (nNRTI) with activity against Human Immunodeficiency Virus Type 1 (HIV-1). HIV-2 RT and eukaryotic DNA polymerases (such as human DNA polymerases alpha, beta, or sigma) are not inhibited by nevirapine. Nevirapine is, in general, only prescribed after the immune system has declined and infections have become evident. It is always taken with at least one other HIV medication such as Retrovir or Videx. The virus can develop resistance to nevirapine if the drug is taken alone, although even if used properly, nevirapine is effective for only a limited time.

Nevirapine Absorption

90% (absolute bioavailability 93 ± 9%)

Nevirapine side effects and Toxicity

Symptoms of overdose include edema, erythema nodosum, fatigue, fever, headache, insomnia, nausea, pulmonaryinfiltrates, rash, vertigo, vomiting, and weight decrease.

Nevirapine Patient Information

Nevirapine Organisms Affected

Human immunodeficiency virus