Naftifine
Naftifine Brand names, Naftifine Analogs
Naftifine Brand Names Mixture
- No information avaliable
Naftifine Chemical_Formula
C21H21N
Naftifine RX_link
http://www.rxlist.com/cgi/generic2/naft.htm
Naftifine fda sheet
Naftifine msds (material safety sheet)
Naftifine Synthesis Reference
No information avaliable
Naftifine Molecular Weight
287.398 g/mol
Naftifine Melting Point
No information avaliable
Naftifine H2O Solubility
No information avaliable
Naftifine State
Solid
Naftifine LogP
5.62
Naftifine Dosage Forms
Cream; Gel (1%)
Naftifine Indication
For the topical treatment of tinea pedis, tinea cruris, and tinea corporis caused by the organisms Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans and Epidermophyton floccosum.
Naftifine Pharmacology
Naftifine is a synthetic, broad spectrum, antifungal agent and allylamine derivative. The following in vitro data are available, but their clinical significance is unknown. Naftifine has been shown to exhibit fungicidal activity in vitro against a broad spectrum of organisms including Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Epidermophyton floccosum, and Microsporum canis, Microsporum audouini, and Microsporum gypseum; and fungistatic activity against Candida species including Candida albicans. However it is only used to treat the organisms listed in the indications.
Naftifine Absorption
Following single topical applications of 3H-labeled naftifine gel 1% to the skin of healthy subjects, up to 4.2% of the applied dose was absorbed.
Naftifine side effects and Toxicity
No information avaliable
Naftifine Patient Information
No information avaliable
Naftifine Organisms Affected
Yeast and other fungi
