Ethmozine
Brand names,
Ethmozine
Analogs
Ethmozine
Brand Names Mixture
Ethmozine
Chemical_Formula
C21H21N
Ethmozine
RX_link
http://www.rxlist.com/cgi/generic2/naft.htm
Ethmozine
fda sheet
Ethmozine
msds (material safety sheet)
Ethmozine
Synthesis Reference
No information avaliable
Ethmozine
Molecular Weight
287.398 g/mol
Ethmozine
Melting Point
No information avaliable
Ethmozine
H2O Solubility
No information avaliable
Ethmozine
State
Solid
Ethmozine
LogP
5.62
Ethmozine
Dosage Forms
Cream; Gel (1%)
Ethmozine
Indication
For the topical treatment of tinea pedis, tinea cruris, and tinea corporis caused by the organisms Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans and Epidermophyton floccosum.
Ethmozine
Pharmacology
Naftifine is a synthetic, broad spectrum, antifungal agent and allylamine derivative. The following in vitro data are available, but their clinical significance is unknown. Naftifine has been shown to exhibit fungicidal activity in vitro against a broad spectrum of organisms including Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Epidermophyton floccosum, and Microsporum canis, Microsporum audouini, and Microsporum gypseum; and fungistatic activity against Candida species including Candida albicans. However it is only used to treat the organisms listed in the indications.
Ethmozine
Absorption
Following single topical applications of 3H-labeled naftifine gel 1% to the skin of healthy subjects, up to 4.2% of the applied dose was absorbed.
Ethmozine
side effects and Toxicity
No information avaliable
Ethmozine
Patient Information
No information avaliable
Ethmozine
Organisms Affected
Yeast and other fungi