Moracizine
Brand names,
Moracizine
Analogs
Moracizine
Brand Names Mixture
Moracizine
Chemical_Formula
C21H21N
Moracizine
RX_link
http://www.rxlist.com/cgi/generic2/naft.htm
Moracizine
fda sheet
Moracizine
msds (material safety sheet)
Moracizine
Synthesis Reference
No information avaliable
Moracizine
Molecular Weight
287.398 g/mol
Moracizine
Melting Point
No information avaliable
Moracizine
H2O Solubility
No information avaliable
Moracizine
State
Solid
Moracizine
LogP
5.62
Moracizine
Dosage Forms
Cream; Gel (1%)
Moracizine
Indication
For the topical treatment of tinea pedis, tinea cruris, and tinea corporis caused by the organisms Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans and Epidermophyton floccosum.
Moracizine
Pharmacology
Naftifine is a synthetic, broad spectrum, antifungal agent and allylamine derivative. The following in vitro data are available, but their clinical significance is unknown. Naftifine has been shown to exhibit fungicidal activity in vitro against a broad spectrum of organisms including Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Epidermophyton floccosum, and Microsporum canis, Microsporum audouini, and Microsporum gypseum; and fungistatic activity against Candida species including Candida albicans. However it is only used to treat the organisms listed in the indications.
Moracizine
Absorption
Following single topical applications of 3H-labeled naftifine gel 1% to the skin of healthy subjects, up to 4.2% of the applied dose was absorbed.
Moracizine
side effects and Toxicity
No information avaliable
Moracizine
Patient Information
No information avaliable
Moracizine
Organisms Affected
Yeast and other fungi