N-Methylscopolammonium Bromide

N-Methylscopolammonium Bromide Brand names, N-Methylscopolammonium Bromide Analogs

N-Methylscopolammonium Bromide Brand Names Mixture

Biosol-M-Aquadrops liq (methscopolamine bromide + neomycin sulfate)
Neomix-pamine Scour Bolus (methscopolamine bromide + neomycin sulfate)
Neomix-pamine Solution (methscopolamine bromide + neomycin sulfate)
Neosol M Aquadrops (methscopolamine bromide + neomycin)
Scour solution (methscopolamine bromide + neomycin)
Scour solution coop (methscopolamine bromide + neomycin)

N-Methylscopolammonium Bromide Chemical_Formula

C₁₈H₂₄NO₄.Br

N-Methylscopolammonium Bromide RX_link

http://www.rxlist.com/cgi/pharmclips2.cgi?keyword=%20Methscopolamine

N-Methylscopolammonium Bromide fda sheet

N-Methylscopolammonium_Bromide FDA

N-Methylscopolammonium Bromide msds (material safety sheet)

N-Methylscopolammonium Bromide Synthesis Reference

No information avaliable

N-Methylscopolammonium Bromide Molecular Weight

397.089 g/mol

N-Methylscopolammonium Bromide Melting Point

225 ^oC

N-Methylscopolammonium Bromide H₂O Solubility

Freely soluble

N-Methylscopolammonium Bromide State

Solid

N-Methylscopolammonium Bromide LogP

-2.58

N-Methylscopolammonium Bromide Dosage Forms

Tablet (2.5mg, 5mg)

N-Methylscopolammonium Bromide Indication

Used as adjunctive therapy for the treatment of peptic ulcer. Also used to treat nausea and vomiting due to motion sickness.

N-Methylscopolammonium Bromide Pharmacology

Methscopolamine bromide is a muscarinic antagonist structurally similar to the neurotransmitter acetylcholine and acts by blocking the muscarinic acetylcholine receptors and is thus classified as an anticholinergic. Methscopolamine bromide has many uses including the prevention of motion sickness. It is not clear how methscopolamine bromide prevents nausea and vomiting due to motion sickness. The vestibular part of the ear is very important for balance. When a person becomes disoriented due to motion, the vestibule sends a signal through nerves to the vomiting center in the brain, and vomiting occurs. Acetylcholine is a chemical that nerves use to transmit messages to each other. It is believe that methscopolamine bromide prevents communication between the nerves of the vestibule and the vomiting center in the brain by blocking the action of acetylcholine. Methscopolamine bromide also may work directly on the vomiting center. Methscopolamine bromide must be taken before the onset of motion sickness to be effective.

N-Methylscopolammonium Bromide Absorption

Poorly and unreliably absorbed, total absorption is 10-25%.

N-Methylscopolammonium Bromide side effects and Toxicity

Symptoms of a methscopolamine bromide overdose include headache, nausea, vomiting, dry mouth, difficulty swallowing, blurred vision, dilated pupils, hot, dry skin, dizziness; drowsiness, confusion, anxiety, seizures, weak pulse, and an irregular heartbeat. In addition, a curare-like action may occur, i.e., neuromuscular blockade leading to muscular weakness and possible paralysis.

N-Methylscopolammonium Bromide Patient Information