Epoxytropine Tropate Methylbromide
Brand names,
Epoxytropine Tropate Methylbromide
Analogs
Epoxytropine Tropate Methylbromide
Brand Names Mixture
- Biosol-M-Aquadrops liq (methscopolamine bromide + neomycin sulfate)
- Neomix-pamine Scour Bolus (methscopolamine bromide + neomycin sulfate)
- Neomix-pamine Solution (methscopolamine bromide + neomycin sulfate)
- Neosol M Aquadrops (methscopolamine bromide + neomycin)
- Scour solution (methscopolamine bromide + neomycin)
- Scour solution coop (methscopolamine bromide + neomycin)
Epoxytropine Tropate Methylbromide
Chemical_Formula
C18H24NO4.Br
Epoxytropine Tropate Methylbromide
RX_link
http://www.rxlist.com/cgi/pharmclips2.cgi?keyword=%20Methscopolamine
Epoxytropine Tropate Methylbromide
fda sheet
Epoxytropine Tropate Methylbromide
msds (material safety sheet)
Epoxytropine Tropate Methylbromide
Synthesis Reference
No information avaliable
Epoxytropine Tropate Methylbromide
Molecular Weight
397.089 g/mol
Epoxytropine Tropate Methylbromide
Melting Point
225 oC
Epoxytropine Tropate Methylbromide
H2O Solubility
Freely soluble
Epoxytropine Tropate Methylbromide
State
Solid
Epoxytropine Tropate Methylbromide
LogP
-2.58
Epoxytropine Tropate Methylbromide
Dosage Forms
Tablet (2.5mg, 5mg)
Epoxytropine Tropate Methylbromide
Indication
Used as adjunctive therapy for the treatment of peptic ulcer. Also used to treat nausea and vomiting due to motion sickness.
Epoxytropine Tropate Methylbromide
Pharmacology
Methscopolamine bromide is a muscarinic antagonist structurally similar to the neurotransmitter acetylcholine and acts by blocking the muscarinic acetylcholine receptors and is thus classified as an anticholinergic. Methscopolamine bromide has many uses including the prevention of motion sickness. It is not clear how methscopolamine bromide prevents nausea and vomiting due to motion sickness. The vestibular part of the ear is very important for balance. When a person becomes disoriented due to motion, the vestibule sends a signal through nerves to the vomiting center in the brain, and vomiting occurs. Acetylcholine is a chemical that nerves use to transmit messages to each other. It is believe that methscopolamine bromide prevents communication between the nerves of the vestibule and the vomiting center in the brain by blocking the action of acetylcholine. Methscopolamine bromide also may work directly on the vomiting center. Methscopolamine bromide must be taken before the onset of motion sickness to be effective.
Epoxytropine Tropate Methylbromide
Absorption
Poorly and unreliably absorbed, total absorption is 10-25%.
Epoxytropine Tropate Methylbromide
side effects and Toxicity
Symptoms of a methscopolamine bromide overdose include headache, nausea, vomiting, dry mouth, difficulty swallowing, blurred vision, dilated pupils, hot, dry skin, dizziness; drowsiness, confusion, anxiety, seizures, weak pulse, and an irregular heartbeat. In addition, a curare-like action may occur, i.e., neuromuscular blockade leading to muscular weakness and possible paralysis.
Epoxytropine Tropate Methylbromide
Patient Information
No information avaliable
Epoxytropine Tropate Methylbromide
Organisms Affected
Humans and other mammals