Metvix
Brand names,
Metvix
Analogs
Metvix
Brand Names Mixture
Metvix
Chemical_Formula
C21H25N5O8S2
Metvix
RX_link
No information avaliable
Metvix
fda sheet
Metvix
msds (material safety sheet)
Metvix
Synthesis Reference
No information avaliable
Metvix
Molecular Weight
539.584 g/mol
Metvix
Melting Point
No information avaliable
Metvix
H2O Solubility
No information avaliable
Metvix
State
Solid
Metvix
LogP
-0.249
Metvix
Dosage Forms
Powder for solution (for IV or IM injection)
Metvix
Indication
Used to treat serious gram–negative infections of the lungs, urinary tract, and skin.
Metvix
Pharmacology
Mezlocillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. The name "penicillin" can either refer to several variants of penicillin available, or to the group of antibiotics derived from the penicillins. Mezlocillin has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria. The bactericidal activity of mezlocillin results from the inhibition of cell wall synthesis and is mediated through mezlocillin binding to penicillin binding proteins (PBPs). Mezlocillin is stable against hydrolysis by a variety of beta-lactamases, including penicillinases, and cephalosporinases and extended spectrum beta-lactamases. Mezlocillin can be used to treat susceptible strains of H. influenzae, Klebsiella species, Pseudomonas species, Proteus mirabilis, E. coli, Enterobacter species, Streptococcus faecelis, Peptococcus species, Peptostreptococcus species, Bacteriodes species (including B. fragilis), Morganella morganii, Serratia species, N. gonorrhoeae, P. vulgaris, and Providencia rettgeri. This drug is discontinued in the U.S.
Metvix
Absorption
No information avaliable
Metvix
side effects and Toxicity
Symptoms of overdose include rash, fever, chills, and peeling skin.
Metvix
Patient Information
Metvix
Organisms Affected
Enteric bacteria and other eubacteria