Methilazine hydrochloride en es it fr

Methilazine hydrochloride Brand names, Methilazine hydrochloride Analogs

Methilazine hydrochloride Brand Names Mixture

  • No information avaliable

Methilazine hydrochloride Chemical_Formula

C18H20N2S

Methilazine hydrochloride RX_link

No information avaliable

Methilazine hydrochloride fda sheet

Methilazine hydrochloride msds (material safety sheet)

Methilazine hydrochloride Synthesis Reference

No information avaliable

Methilazine hydrochloride Molecular Weight

296.431 g/mol

Methilazine hydrochloride Melting Point

87-88 oC

Methilazine hydrochloride H2O Solubility

0.348 mg/L

Methilazine hydrochloride State

Solid

Methilazine hydrochloride LogP

4.781

Methilazine hydrochloride Dosage Forms

Syrup; Tablets; Chewable tablets

Methilazine hydrochloride Indication

Used for the symptomatic relief of hypersensitivity reactions and particularly for the control of pruritic skin disorders

Methilazine hydrochloride Pharmacology

In allergic reactions an allergen interacts with and cross-links surface IgE antibodies on mast cells and basophils. Once the mast cell-antibody-antigen complex is formed, a complex series of events occurs that eventually leads to cell-degranulation and the release of histamine (and other chemical mediators) from the mast cell or basophil. Once released, histamine can react with local or widespread tissues through histamine receptors. Histamine, acting on H1-receptors, produces pruritis, vasodilatation, hypotension, flushing, headache, tachycardia, and bronchoconstriction. Histamine also increases vascular permeability and potentiates pain. Methdilazine is a histamine H1 antagonist. It competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract. It provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose due to hay fever and other upper respiratory allergies.

Methilazine hydrochloride Absorption

Well absorbed in the digestive tract.

Methilazine hydrochloride side effects and Toxicity

Symptoms of overdose include clumsiness or unsteadiness, convulsions, drowsiness, dryness of mouth, nose, or throat, feeling faint, flushing or redness of face, hallucinations, muscle spasms (especially of neck and back), restlessness, shortness of breath or troubled breathing, shuffling walk, tic-like movements of head and face, trembling and shaking of hands, and trouble in sleeping.

Methilazine hydrochloride Patient Information

No information avaliable

Methilazine hydrochloride Organisms Affected

Humans and other mammals