Meropenem
Meropenem Brand names, Meropenem Analogs
Meropenem Brand Names Mixture
- No information avaliable
Meropenem Chemical_Formula
C17H25N3O5S
Meropenem RX_link
http://www.rxlist.com/cgi/generic2/meropen.htm
Meropenem fda sheet
Meropenem msds (material safety sheet)
Meropenem Synthesis Reference
No information avaliable
Meropenem Molecular Weight
383.464 g/mol
Meropenem Melting Point
No information avaliable
Meropenem H2O Solubility
Sparingly
Meropenem State
Solid
Meropenem LogP
0.33
Meropenem Dosage Forms
Powder for solution (for injection)
Meropenem Indication
For use as single agent therapy for the treatment of the following infections when caused by susceptible isolates of the designated microorganisms: complicated skin and skin structure infections due to Staphylococcus aureus (b-lactamase and non-b-lactamase producing, methicillin-susceptible isolates only), Streptococcus pyogenes, Streptococcus agalactiae, viridans group streptococci, Enterococcus faecalis (excluding vancomycin-resistant isolates), Pseudomonas aeruginosa, Escherichia coli, Proteus mirabilis, Bacteroides fragilis and Peptostreptococcus species; complicated appendicitis and peritonitis caused by viridans group streptococci, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Bacteroides fragilis, B. thetaiotaomicron, and Peptostreptococcus species. Also for use in the treatment of bacterial meningitis caused by Streptococcus pneumoniae, Haemophilus influenzae (b-lactamase and non-b-lactamase-producing isolates), and Neisseria meningitidis.
Meropenem Pharmacology
Meropenem is a broad-spectrum carbapenem antibiotic. It is active against Gram-positive and Gram-negative bacteria. Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis of vital cell wall components, which leads to cell death.
Meropenem Absorption
No information avaliable
Meropenem side effects and Toxicity
In mice and rats, large intravenous doses of meropenem (2200-4000 mg/kg) have been associated with ataxia, dyspnea, convulsions, and mortalities.
Meropenem Patient Information
Meropenem Organisms Affected
Enteric bacteria and other eubacteria
