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Mecloprodin Brand names, Mecloprodin Analogs

Mecloprodin Brand Names Mixture

  • Xalacom (Latanoprost + Timolol Maleate)

Mecloprodin Chemical_Formula


Mecloprodin RX_link

Mecloprodin fda sheet

Mecloprodin msds (material safety sheet)

Mecloprodin MSDS

Mecloprodin Synthesis Reference

No information avaliable

Mecloprodin Molecular Weight

343.89 g/mol

Mecloprodin Melting Point

178 oC (hydrogen fumarate formulation)

Mecloprodin H2O Solubility

Soluble (hydrogen fumarate formulation)

Mecloprodin State


Mecloprodin LogP


Mecloprodin Dosage Forms

Syrup (0.5 mg drug per 5mL syrup) and tablet (oral, 1mg)

Mecloprodin Indication

For the relief of symptoms associated with allergic rhinitis such as sneezing, rhinorrhea, pruritus and acrimation.

Mecloprodin Pharmacology

Clemastine is an antihistamine with anticholinergic (drying) and sedative side effects. Antihistamines competitively antagonize various physiological effects of histamine including increased capillary permeability and dilatation, the formation of edema, the "flare" and "itch" response, and gastrointestinal and respiratory smooth muscle constriction. Within the vascular tree, H1- receptor antagonists inhibit both the vasoconstrictor and vasodilator effects of histamine. Depending on the dose, H1- receptor antagonists can produce CNS stimulation or depression. Most antihistamines exhibit central and/or peripheral anticholinergic activity. Antihistamines act by competitively blocking H1- receptor sites. Antihistamines do not pharmacologically antagonize or chemically inactivate histamine, nor do they prevent the release of histamine.

Mecloprodin Absorption

Rapidly absorbed from the gastrointestinal tract.

Mecloprodin side effects and Toxicity

Oral LD50 in rat and mouse is 3550 mg/kg and 730 mg/kg, respectively. Antihistamine overdosage reactions may vary from central nervous system depression to stimulation. In children, stimulation predominates initially in a syndrome which may include excitement, hallucinations, ataxia, incoordination, muscle twitching, athetosis, hyperthermia, cyanosis convulsions, tremors, and hyperreflexia followed by postictal depression and cardio-respiratory arrest. Convulsions in children may be preceded by mild depression. Dry mouth, fixed dilated pupils, flushing of the face, and fever are common. In adults, CNS depression, ranging from drowsiness to coma, is more common.

Mecloprodin Patient Information

No information avaliable

Mecloprodin Organisms Affected

Humans and other mammals