Mecamylamine

• Antihypertensive Agents
• Nicotinic Receptor Antagonist ATC:C02BB01

• 2-Methylamino-2,3,3-trimethylnorbornane
• 2-Methylaminoisocamphane
• 2-Norbornanamine, N,2,3,3-tetramethyl-
• 2-Norbornanamine, N,2,3,3-tetramethyl-, hydrochloride
• 3-Methylaminoisocamphane
• 3-Methylaminoisocamphane hydrochloride
• Inversine
• Inversine hydrochloride
• Mecamilamina
• Mecamine
• Mecamine hydrochloride
• Mecamylamine Hydrochloride
• Mekamin hydrochloride
• Mekamine
• Mevasin hydrochloride
• Mevasine
• Revertina
• Versamine

• No information avaliable

C₁₁H₂₁N

http://www.rxlist.com/cgi/generic2/mecamylamine.htm

No information avaliable

167.291 g/mol

<25 ^oC

No information avaliable

Liquid

2.477

Tablets

For the treatment of moderately severe to severe essential hypertension and in uncomplicated cases of malignant hypertension

Mecamylamine is a potent, oral antihypertensive agent and ganglion blocker, and is a secondary amine. Mecamylamine is indicated for the management of moderately severe to severe essential hypertension and in uncomplicated cases of malignant hypertension. Mecamylamine reduces blood pressure in both normotensive and hypertensive individuals. A small oral dosage often produces a smooth and predictable reduction of blood pressure. Although this antihypertensive effect is predominantly orthostatic, the supine blood pressure is also significantly reduced. Mecamylamine crosses the blood-brain and placental barriers.

Mecamylamine is almost completely absorbed from the gastrointestinal tract

No information avaliable

APRD00458_PI.txt

Humans and other mammals