Lomefloxacin

Lomefloxacin Brand names, Lomefloxacin Analogs

Lomefloxacin Brand Names Mixture

No information avaliable

Lomefloxacin Chemical_Formula

C₁₇H₁₉F₂N₃O₃

Lomefloxacin RX_link

http://www.rxlist.com/cgi/generic2/lomefloxacin.htm

Lomefloxacin fda sheet

Lomefloxacin FDA

Lomefloxacin msds (material safety sheet)

Lomefloxacin Synthesis Reference

No information avaliable

Lomefloxacin Molecular Weight

351.348 g/mol

Lomefloxacin Melting Point

239-240.5 ^oC

Lomefloxacin H₂O Solubility

27.2 mg/mL

Lomefloxacin State

Solid

Lomefloxacin LogP

1.781

Lomefloxacin Dosage Forms

Tablet

Lomefloxacin Indication

For the treatment of bacterial infections of the respiratory tract (chronic bronchitis) and urinary tract, and as a pre-operative prophylactic to prevent urinary tract infection caused by: S.pneumoniae, H.influenzae, S.aureus, P.aeruginosa, E. cloacae, P. mirabilis, C. civersus, S. asprphyticus, E.coli, and K.pneumoniae.

Lomefloxacin Pharmacology

Lomefloxacin is a fluoroquinolone antibiotic used to treat chronic bronchitis, as well as complicated and uncomplicated urinary tract infections. It is also used as a prophylactic or preventative treatment to prevent urinary tract infections in patients undergoing transrectal or transurethral surgical procedures. Flouroquinolones such as lomefloxacin possess excellent activity against gram-negative aerobic bacteria such as E.coli and Neisseria gonorrhoea as well as gram-positive bacteria including S. pneumoniae and Staphylococcus aureus. They also posses effective activity against shigella, salmonella, campylobacter, gonococcal organisms, and multi drug resistant pseudomonas and enterobacter.

Lomefloxacin Absorption

Rapid and nearly complete with approximately 95% to 98% of a single oral dose being absorbed.

Lomefloxacin side effects and Toxicity

Adverse reactions include peripheral neuropathy, nervousness, agitation, anxiety, and phototoxic events (rash, itching, burning) due to sunlight exposure.

Lomefloxacin Patient Information

Lomefloxacin Organisms Affected

Enteric bacteria and other eubacteria