Levocabastin
Brand names,
Levocabastin
Analogs
Levocabastin
Brand Names Mixture
Levocabastin
Chemical_Formula
C17H19F2N3O3
Levocabastin
RX_link
http://www.rxlist.com/cgi/generic2/lomefloxacin.htm
Levocabastin
fda sheet
Levocabastin
msds (material safety sheet)
Levocabastin
Synthesis Reference
No information avaliable
Levocabastin
Molecular Weight
351.348 g/mol
Levocabastin
Melting Point
239-240.5 oC
Levocabastin
H2O Solubility
27.2 mg/mL
Levocabastin
State
Solid
Levocabastin
LogP
1.781
Levocabastin
Dosage Forms
Tablet
Levocabastin
Indication
For the treatment of bacterial infections of the respiratory tract (chronic bronchitis) and urinary tract, and as a pre-operative prophylactic to prevent urinary tract infection caused by: S.pneumoniae, H.influenzae, S.aureus, P.aeruginosa, E. cloacae, P. mirabilis, C. civersus, S. asprphyticus, E.coli, and K.pneumoniae.
Levocabastin
Pharmacology
Lomefloxacin is a fluoroquinolone antibiotic used to treat chronic bronchitis, as well as complicated and uncomplicated urinary tract infections. It is also used as a prophylactic or preventative treatment to prevent urinary tract infections in patients undergoing transrectal or transurethral surgical procedures. Flouroquinolones such as lomefloxacin possess excellent activity against gram-negative aerobic bacteria such as E.coli and Neisseria gonorrhoea as well as gram-positive bacteria including S. pneumoniae and Staphylococcus aureus. They also posses effective activity against shigella, salmonella, campylobacter, gonococcal organisms, and multi drug resistant pseudomonas and enterobacter.
Levocabastin
Absorption
Rapid and nearly complete with approximately 95% to 98% of a single oral dose being absorbed.
Levocabastin
side effects and Toxicity
Adverse reactions include peripheral neuropathy, nervousness, agitation, anxiety, and phototoxic events (rash, itching, burning) due to sunlight exposure.
Levocabastin
Patient Information
Levocabastin
Organisms Affected
Enteric bacteria and other eubacteria