Livostin
Brand names,
Livostin
Analogs
Livostin
Brand Names Mixture
Livostin
Chemical_Formula
C17H19F2N3O3
Livostin
RX_link
http://www.rxlist.com/cgi/generic2/lomefloxacin.htm
Livostin
fda sheet
Livostin
msds (material safety sheet)
Livostin
Synthesis Reference
No information avaliable
Livostin
Molecular Weight
351.348 g/mol
Livostin
Melting Point
239-240.5 oC
Livostin
H2O Solubility
27.2 mg/mL
Livostin
State
Solid
Livostin
LogP
1.781
Livostin
Dosage Forms
Tablet
Livostin
Indication
For the treatment of bacterial infections of the respiratory tract (chronic bronchitis) and urinary tract, and as a pre-operative prophylactic to prevent urinary tract infection caused by: S.pneumoniae, H.influenzae, S.aureus, P.aeruginosa, E. cloacae, P. mirabilis, C. civersus, S. asprphyticus, E.coli, and K.pneumoniae.
Livostin
Pharmacology
Lomefloxacin is a fluoroquinolone antibiotic used to treat chronic bronchitis, as well as complicated and uncomplicated urinary tract infections. It is also used as a prophylactic or preventative treatment to prevent urinary tract infections in patients undergoing transrectal or transurethral surgical procedures. Flouroquinolones such as lomefloxacin possess excellent activity against gram-negative aerobic bacteria such as E.coli and Neisseria gonorrhoea as well as gram-positive bacteria including S. pneumoniae and Staphylococcus aureus. They also posses effective activity against shigella, salmonella, campylobacter, gonococcal organisms, and multi drug resistant pseudomonas and enterobacter.
Livostin
Absorption
Rapid and nearly complete with approximately 95% to 98% of a single oral dose being absorbed.
Livostin
side effects and Toxicity
Adverse reactions include peripheral neuropathy, nervousness, agitation, anxiety, and phototoxic events (rash, itching, burning) due to sunlight exposure.
Livostin
Patient Information
Livostin
Organisms Affected
Enteric bacteria and other eubacteria