Lodine

Lodine Brand names, Lodine Analogs

Lodine Brand Names Mixture

No information avaliable

Lodine Chemical_Formula

C₁₇H₂₁NO₃

Lodine RX_link

http://www.rxlist.com/cgi/generic/etodolac.htm

Lodine fda sheet

Lodine FDA

Lodine msds (material safety sheet)

Lodine Synthesis Reference

C. A. Demerson et al., U.S. Pat. 3,939,178 (1976)

Lodine Molecular Weight

287.354 g/mol

Lodine Melting Point

145-148 ^oC

Lodine H₂O Solubility

16 mg/L

Lodine State

Solid

Lodine LogP

No information avaliable

Lodine Dosage Forms

Tablet; Tablet (extended-release)

Lodine Indication

For acute and long-term use in the management of signs and symptoms of osteoarthritis and rheumatoid arthritis, as well as for the management of pain.

Lodine Pharmacology

Etodolac, an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain.

Lodine Absorption

Based on mass balance studies, the systemic availability of etodolac from either the tablet or capsule formulation, is at least 80%.

Lodine side effects and Toxicity

Symptoms of overdose include lethargy, drowsiness, nausea, vomiting, and epigastric pain.

Lodine Patient Information

Lodine, like other drugs of its class, can cause discomfort and, rarely, more serious side effects, such as gastrointestinal bleeding, which may result in hospitalization and even fatal outcomes. Although serious GI tract ulcerations and bleeding can occur without warning symptoms, patients should be alert for the signs and symptoms of ulcerations and bleeding, and should ask for medical advice when observing any indicative sign or symptom. Patients should be informed of the importance of this follow-up Effects Risk of GI Ulceration, Bleeding, and Perforation).

Patients on Lodine (etodolac capsules and tablets) should report to their physicians signs or symptoms of gastrointestinal ulceration or bleeding, blurred vision or other eye symptoms, skin rash, weight gain, or edema.

Patients should also be instructed to seek medical emergency help in case of an occurrence of anaphylactoid reactions.

Lodine Organisms Affected

Humans and other mammals