Etodolacetodolic acid
Brand names,
Etodolacetodolic acid
Analogs
Etodolacetodolic acid
Brand Names Mixture
Etodolacetodolic acid
Chemical_Formula
C17H21NO3
Etodolacetodolic acid
RX_link
http://www.rxlist.com/cgi/generic/etodolac.htm
Etodolacetodolic acid
fda sheet
Etodolacetodolic acid
msds (material safety sheet)
Etodolacetodolic acid
Synthesis Reference
C. A. Demerson et al., U.S. Pat. 3,939,178 (1976)
Etodolacetodolic acid
Molecular Weight
287.354 g/mol
Etodolacetodolic acid
Melting Point
145-148 oC
Etodolacetodolic acid
H2O Solubility
16 mg/L
Etodolacetodolic acid
State
Solid
Etodolacetodolic acid
LogP
No information avaliable
Etodolacetodolic acid
Dosage Forms
Tablet; Tablet (extended-release)
Etodolacetodolic acid
Indication
For acute and long-term use in the management of signs and symptoms of osteoarthritis and rheumatoid arthritis, as well as for the management of pain.
Etodolacetodolic acid
Pharmacology
Etodolac, an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain.
Etodolacetodolic acid
Absorption
Based on mass balance studies, the systemic availability of etodolac from either the tablet or capsule formulation, is at least 80%.
Etodolacetodolic acid
side effects and Toxicity
Symptoms of overdose include lethargy, drowsiness, nausea, vomiting, and epigastric pain.
Etodolacetodolic acid
Patient Information
Lodine, like other drugs of its class, can cause discomfort and, rarely, more serious side effects, such as
gastrointestinal bleeding, which may result in hospitalization and even fatal outcomes. Although serious GI tract
ulcerations and bleeding can occur without warning symptoms, patients should be alert for the signs and symptoms of
ulcerations and bleeding, and should ask for medical advice when observing any indicative sign or symptom. Patients
should be informed of the importance of this follow-up Effects Risk of GI Ulceration, Bleeding, and
Perforation).
Patients on Lodine (etodolac capsules and tablets) should report to their physicians signs or symptoms of
gastrointestinal ulceration or bleeding, blurred vision or other eye symptoms, skin rash, weight gain, or edema.
Patients should also be instructed to seek medical emergency help in case of an occurrence of anaphylactoid
reactions.
Etodolacetodolic acid
Organisms Affected
Humans and other mammals