Lipiodol
Brand names,
Lipiodol
Analogs
Lipiodol
Brand Names Mixture
Lipiodol
Chemical_Formula
C23H30O3
Lipiodol
RX_link
No information avaliable
Lipiodol
fda sheet
Lipiodol
msds (material safety sheet)
Lipiodol
Synthesis Reference
No information avaliable
Lipiodol
Molecular Weight
354.483 g/mol
Lipiodol
Melting Point
No information avaliable
Lipiodol
H2O Solubility
No information avaliable
Lipiodol
State
Solid
Lipiodol
LogP
5.59
Lipiodol
Dosage Forms
Tablet
Lipiodol
Indication
For the treatment of severe psoriasis in adults.
Lipiodol
Pharmacology
The active metabolite responsible for etretinate's effects, acitretin, is a retinoid. Retinoids have a structure similar to vitamin A and are involved in the normal growth of skin cells. Acitretin works by inhibiting the excessive cell growth and keratinisation (process by which skin cells become thickened due to the deposition of a protein within them) seen in psoriasis. It therefore reduces the thickening of the skin, plaque formation and scaling.
Lipiodol
Absorption
Absorbed in the small intestine. Studies in normal volunteers indicate that the absorption of etretinate is greater in patients consuming whole milk or a high-fat diet than in patients in a fasting state.
Lipiodol
side effects and Toxicity
Symptoms of overdose include headache and vertigo.
Lipiodol
Patient Information
Lipiodol
Organisms Affected
Humans and other mammals