EOE 13
EOE 13 Brand names, EOE 13 Analogs
EOE 13 Brand Names Mixture
- No information avaliable
EOE 13 Chemical_Formula
C23H30O3
EOE 13 RX_link
No information avaliable
EOE 13 fda sheet
EOE 13 msds (material safety sheet)
EOE 13 Synthesis Reference
No information avaliable
EOE 13 Molecular Weight
354.483 g/mol
EOE 13 Melting Point
No information avaliable
EOE 13 H2O Solubility
No information avaliable
EOE 13 State
Solid
EOE 13 LogP
5.59
EOE 13 Dosage Forms
Tablet
EOE 13 Indication
For the treatment of severe psoriasis in adults.
EOE 13 Pharmacology
The active metabolite responsible for etretinate's effects, acitretin, is a retinoid. Retinoids have a structure similar to vitamin A and are involved in the normal growth of skin cells. Acitretin works by inhibiting the excessive cell growth and keratinisation (process by which skin cells become thickened due to the deposition of a protein within them) seen in psoriasis. It therefore reduces the thickening of the skin, plaque formation and scaling.
EOE 13 Absorption
Absorbed in the small intestine. Studies in normal volunteers indicate that the absorption of etretinate is greater in patients consuming whole milk or a high-fat diet than in patients in a fasting state.
EOE 13 side effects and Toxicity
Symptoms of overdose include headache and vertigo.
EOE 13 Patient Information
EOE 13 Organisms Affected
Humans and other mammals
