Lepirudin
Lepirudin Brand names, Lepirudin Analogs
Lepirudin Brand Names Mixture
- No information avaliable
Lepirudin Chemical_Formula
C288H448N80O110S6
Lepirudin RX_link
http://www.rxlist.com/cgi/generic3/lepirudin.htm
Lepirudin fda sheet
Lepirudin msds (material safety sheet)
Lepirudin Synthesis Reference
No information avaliable
Lepirudin Molecular Weight
6983.5
Lepirudin Melting Point
65 oC (Otto, A. & Seckler, R. Eur. J. Biochem. 202:67-73 (1991))
Lepirudin H2O Solubility
No information avaliable
Lepirudin State
Liquid
Lepirudin LogP
-0.777
Lepirudin Dosage Forms
Powder for solution; Solution (IV infusion and injection)
Lepirudin Indication
For the treatment of heparin-induced thrombocytopenia
Lepirudin Pharmacology
Lepirudin is used to break up clots and to reduce thrombocytopenia. It binds to thrombin and prevents thrombus or clot formation. It is a highly potent, selective, and essentially irreversible inhibitor of thrombin and clot-bond thrombin. Lepirudin requires no cofactor for its anticoagulant action.
Lepirudin Absorption
No information avaliable
Lepirudin side effects and Toxicity
No information avaliable
Lepirudin Patient Information
BIOD00024.html
Lepirudin Organisms Affected
Humans and other mammals
