Refludan (Berlex Labs)
Refludan (Berlex Labs) Brand names, Refludan (Berlex Labs) Analogs
Refludan (Berlex Labs) Brand Names Mixture
- No information avaliable
Refludan (Berlex Labs) Chemical_Formula
C288H448N80O110S6
Refludan (Berlex Labs) RX_link
http://www.rxlist.com/cgi/generic3/lepirudin.htm
Refludan (Berlex Labs) fda sheet
Refludan (Berlex Labs) msds (material safety sheet)
Refludan (Berlex Labs) Synthesis Reference
No information avaliable
Refludan (Berlex Labs) Molecular Weight
6983.5
Refludan (Berlex Labs) Melting Point
65 oC (Otto, A. & Seckler, R. Eur. J. Biochem. 202:67-73 (1991))
Refludan (Berlex Labs) H2O Solubility
No information avaliable
Refludan (Berlex Labs) State
Liquid
Refludan (Berlex Labs) LogP
-0.777
Refludan (Berlex Labs) Dosage Forms
Powder for solution; Solution (IV infusion and injection)
Refludan (Berlex Labs) Indication
For the treatment of heparin-induced thrombocytopenia
Refludan (Berlex Labs) Pharmacology
Lepirudin is used to break up clots and to reduce thrombocytopenia. It binds to thrombin and prevents thrombus or clot formation. It is a highly potent, selective, and essentially irreversible inhibitor of thrombin and clot-bond thrombin. Lepirudin requires no cofactor for its anticoagulant action.
Refludan (Berlex Labs) Absorption
No information avaliable
Refludan (Berlex Labs) side effects and Toxicity
No information avaliable
Refludan (Berlex Labs) Patient Information
BIOD00024.html
Refludan (Berlex Labs) Organisms Affected
Humans and other mammals
