Hirudin variant-1
Brand names,
Hirudin variant-1
Analogs
Hirudin variant-1
Brand Names Mixture
Hirudin variant-1
Chemical_Formula
C288H448N80O110S6
Hirudin variant-1
RX_link
http://www.rxlist.com/cgi/generic3/lepirudin.htm
Hirudin variant-1
fda sheet
Hirudin variant-1
msds (material safety sheet)
Hirudin variant-1
Synthesis Reference
No information avaliable
Hirudin variant-1
Molecular Weight
6983.5
Hirudin variant-1
Melting Point
65 oC (Otto, A. & Seckler, R. Eur. J. Biochem. 202:67-73 (1991))
Hirudin variant-1
H2O Solubility
No information avaliable
Hirudin variant-1
State
Liquid
Hirudin variant-1
LogP
-0.777
Hirudin variant-1
Dosage Forms
Powder for solution; Solution (IV infusion and injection)
Hirudin variant-1
Indication
For the treatment of heparin-induced thrombocytopenia
Hirudin variant-1
Pharmacology
Lepirudin is used to break up clots and to reduce thrombocytopenia. It binds to thrombin and prevents thrombus or clot formation. It is a highly potent, selective, and essentially irreversible inhibitor of thrombin and clot-bond thrombin. Lepirudin requires no cofactor for its anticoagulant action.
Hirudin variant-1
Absorption
No information avaliable
Hirudin variant-1
side effects and Toxicity
No information avaliable
Hirudin variant-1
Patient Information
BIOD00024.html
Hirudin variant-1
Organisms Affected
Humans and other mammals