Lactulose
Brand names,
Lactulose
Analogs
Lactulose
Brand Names Mixture
Lactulose
Chemical_Formula
C12H22O11
Lactulose
RX_link
http://www.rxlist.com/cgi/generic2/lactulose.htm
Lactulose
fda sheet
Lactulose
msds (material safety sheet)
Lactulose
Synthesis Reference
No information avaliable
Lactulose
Molecular Weight
342.296 g/mol
Lactulose
Melting Point
173 - 178 oC
Lactulose
H2O Solubility
764 mg/mL
Lactulose
State
Solid
Lactulose
LogP
-5.19
Lactulose
Dosage Forms
Liquid; Powder; Solution; Syrup
Lactulose
Indication
For the treatment of constipation and hepatic encephalopathy.
Lactulose
Pharmacology
Therapeutically, lactulose has laxative and ammonia-detoxifying actions. In treating constipation lactulose metabolites draw water into the bowel, causing a cathartic effect through osmotic action.
Lactulose
Absorption
Poorly absorbed from the gastrointestinal tract as no human enzyme that is capable of hydrolysis of this disaccharide is present in human gastrointestinal tissue.
Lactulose
side effects and Toxicity
LD50=18.2 g/kg (oral, rat). Side effects include diarrhea and resultant dehydration.
Lactulose
Patient Information
http://www.drugs.com/MTM/labetalol.html
Lactulose
Organisms Affected
Humans and other mammals