L-Norgestrel
Brand names,
L-Norgestrel
Analogs
L-Norgestrel
Brand Names Mixture
- Alesse 21 Tablets (Ethinyl Estradiol + Levonorgestrel)
- Alesse 28 Tablets (Ethinyl Estradiol + Levonorgestrel)
- Min-Ovral 21 (Ethinyl Estradiol + Levonorgestrel)
- Min-Ovral 21 Tab (Ethinyl Estradiol + Levonorgestrel)
- Min-Ovral 28 (Ethinyl Estradiol + Levonorgestrel)
- Min-Ovral 28 Tab (Ethinyl Estradiol + Levonorgestrel)
- Preven Tablets (Ethinyl Estradiol + Levonorgestrel)
- Triphasil 21 (Ethinyl Estradiol + Levonorgestrel)
- Triphasil 21 Tab (Ethinyl Estradiol + Levonorgestrel)
- Triphasil 28 (Ethinyl Estradiol + Levonorgestrel)
- Triphasil 28 Tab (Ethinyl Estradiol + Levonorgestrel)
- Triquilar 21 Tab (Ethinyl Estradiol + Levonorgestrel)
- Triquilar 28 Tab (Ethinyl Estradiol + Levonorgestrel)
L-Norgestrel
Chemical_Formula
C21H28O2
L-Norgestrel
RX_link
http://www.rxlist.com/cgi/generic2/norplant.htm
L-Norgestrel
fda sheet
L-Norgestrel
msds (material safety sheet)
L-Norgestrel
Synthesis Reference
No information avaliable
L-Norgestrel
Molecular Weight
312.446 g/mol
L-Norgestrel
Melting Point
240 oC
L-Norgestrel
H2O Solubility
2.05 mg/L
L-Norgestrel
State
Solid
L-Norgestrel
LogP
3.251
L-Norgestrel
Dosage Forms
Implant; Insert (extended-release); Tablet
L-Norgestrel
Indication
For the treatment of menopausal and postmenopausal disorders and alone or in combination with other hormones as an oral contraceptive.
L-Norgestrel
Pharmacology
L-Norgestrel is used as a female contraceptive. L-Norgestrel is a progestin or a synthetic form of the naturally occurring female sex hormone, progesterone. In a woman's normal menstrual cycle, an egg matures and is released from the ovaries (ovulation). The ovary then produces progesterone, preventing the release of further eggs and priming the lining of the womb for a possible pregnancy. If pregnancy occurs, progesterone levels in the body remain high, maintaining the womb lining. If pregnancy does not occur, progesterone levels in the body fall, resulting in a menstrual period. L-Norgestrel tricks the body processes into thinking that ovulation has already occurred, by maintaining high levels of the synthetic progesterone. This prevents the release of eggs from the ovaries.
L-Norgestrel
Absorption
Levonorgestrel is not subjected to a "first-pass" effect and is virtually 100% bioavailable.
L-Norgestrel
side effects and Toxicity
LD50>5000 mg/kg (orally in rats)
L-Norgestrel
Patient Information
No information avaliable
L-Norgestrel
Organisms Affected
Humans and other mammals