Korbutone
Brand names,
Korbutone
Analogs
Korbutone
Brand Names Mixture
Korbutone
Chemical_Formula
C28H37ClO7
Korbutone
RX_link
http://www.rxlist.com/cgi/generic2/qvar.htm
Korbutone
fda sheet
Korbutone
msds (material safety sheet)
Korbutone
Synthesis Reference
U.S. Pat. 3,312,590 (1967)
Korbutone
Molecular Weight
521.042 g/mol
Korbutone
Melting Point
117-120oC
Korbutone
H2O Solubility
49.39 mg/L
Korbutone
State
Solid
Korbutone
LogP
3.795
Korbutone
Dosage Forms
Oral inhalation; Nasal inhalation; Nasal spray
Korbutone
Indication
For the maintenance treatment of asthma as prophylactic therapy in patients 5 years of age and older
Korbutone
Pharmacology
Beclomethasone, a synthetic halogenated glucocorticoid with antiinflammatory and vasoconstrictive effects, is used for treating steroid-dependent asthma, allergic or nonallergic rhinitis, or recurrent nasal polyps.
Korbutone
Absorption
Mean peak plasma concentration was 88pg/ml at 0.5 hour
Korbutone
side effects and Toxicity
The acute toxicity of beclomethasone dipropionate is low. The only harmful effect that follows inhalation of large amounts of the drug over a short period of time is suppression of hypothalamic-pituitary-adrenal (HPA) function. Chronic: The excessive use of beclomethasone dipropionate over a long period could lead to adrenal suppression.
Korbutone
Patient Information
Korbutone
Organisms Affected
Humans and other mammals