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Korbutone Brand names, Korbutone Analogs

Korbutone Brand Names Mixture

  • none

Korbutone Chemical_Formula

C28H37ClO7

Korbutone RX_link

http://www.rxlist.com/cgi/generic2/qvar.htm

Korbutone fda sheet

Korbutone FDA

Korbutone msds (material safety sheet)

Korbutone Synthesis Reference

U.S. Pat. 3,312,590 (1967)

Korbutone Molecular Weight

521.042 g/mol

Korbutone Melting Point

117-120oC

Korbutone H2O Solubility

49.39 mg/L

Korbutone State

Solid

Korbutone LogP

3.795

Korbutone Dosage Forms

Oral inhalation; Nasal inhalation; Nasal spray

Korbutone Indication

For the maintenance treatment of asthma as prophylactic therapy in patients 5 years of age and older

Korbutone Pharmacology

Beclomethasone, a synthetic halogenated glucocorticoid with antiinflammatory and vasoconstrictive effects, is used for treating steroid-dependent asthma, allergic or nonallergic rhinitis, or recurrent nasal polyps.

Korbutone Absorption

Mean peak plasma concentration was 88pg/ml at 0.5 hour

Korbutone side effects and Toxicity

The acute toxicity of beclomethasone dipropionate is low. The only harmful effect that follows inhalation of large amounts of the drug over a short period of time is suppression of hypothalamic-pituitary-adrenal (HPA) function. Chronic: The excessive use of beclomethasone dipropionate over a long period could lead to adrenal suppression.

Korbutone Patient Information

Korbutone Organisms Affected

Humans and other mammals