Isoflurane
Brand names,
Isoflurane
Analogs
Isoflurane
Brand Names Mixture
Isoflurane
Chemical_Formula
C3H2ClF5O
Isoflurane
RX_link
http://www.rxlist.com/cgi/generic3/isoflurane.htm
Isoflurane
fda sheet
Isoflurane
msds (material safety sheet)
Isoflurane
Synthesis Reference
No information avaliable
Isoflurane
Molecular Weight
184.492 g/mol
Isoflurane
Melting Point
49 oC (BP)
Isoflurane
H2O Solubility
Insoluble
Isoflurane
State
Liquid
Isoflurane
LogP
2.677
Isoflurane
Dosage Forms
Liquid
Isoflurane
Indication
For induction and maintenance of general anesthesia.
Isoflurane
Pharmacology
Isoflurane is a general inhalation anesthetic used for induction and maintenance of general anesthesia. It induces muscle relaxation and reduces pains sensitivity by altering tissue excitability. It does so by decreasing the extent of gap junction mediated cell-cell coupling and altering the activity of the channels that underlie the action potential.
Isoflurane
Absorption
No information avaliable
Isoflurane
side effects and Toxicity
LC50=15300 ppm/3 hrs (inhalation by rat)
Isoflurane
Patient Information
Isoflurane, as well as other general anesthetics, may cause a slight decrease in intellectual function for 2 or 3
days following anesthesia. As with other anesthetics, small changes in moods and symptoms may persist for up to 6
days after administration.
Isoflurane
Organisms Affected
Humans and other mammals