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Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
C3H2ClF5O
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RX_link
http://www.rxlist.com/cgi/generic3/isoflurane.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
184.492 g/mol
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Melting Point
49 oC (BP)
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H2O Solubility
Insoluble
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State
Liquid
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LogP
2.677
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Dosage Forms
Liquid
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Indication
For induction and maintenance of general anesthesia.
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Pharmacology
Isoflurane is a general inhalation anesthetic used for induction and maintenance of general anesthesia. It induces muscle relaxation and reduces pains sensitivity by altering tissue excitability. It does so by decreasing the extent of gap junction mediated cell-cell coupling and altering the activity of the channels that underlie the action potential.
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Absorption
No information avaliable
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side effects and Toxicity
LC50=15300 ppm/3 hrs (inhalation by rat)
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Patient Information
Isoflurane, as well as other general anesthetics, may cause a slight decrease in intellectual function for 2 or 3
days following anesthesia. As with other anesthetics, small changes in moods and symptoms may persist for up to 6
days after administration.
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Organisms Affected
Humans and other mammals