Aerrane
Brand names,
Aerrane
Analogs
Aerrane
Brand Names Mixture
Aerrane
Chemical_Formula
C3H2ClF5O
Aerrane
RX_link
http://www.rxlist.com/cgi/generic3/isoflurane.htm
Aerrane
fda sheet
Aerrane
msds (material safety sheet)
Aerrane
Synthesis Reference
No information avaliable
Aerrane
Molecular Weight
184.492 g/mol
Aerrane
Melting Point
49 oC (BP)
Aerrane
H2O Solubility
Insoluble
Aerrane
State
Liquid
Aerrane
LogP
2.677
Aerrane
Dosage Forms
Liquid
Aerrane
Indication
For induction and maintenance of general anesthesia.
Aerrane
Pharmacology
Isoflurane is a general inhalation anesthetic used for induction and maintenance of general anesthesia. It induces muscle relaxation and reduces pains sensitivity by altering tissue excitability. It does so by decreasing the extent of gap junction mediated cell-cell coupling and altering the activity of the channels that underlie the action potential.
Aerrane
Absorption
No information avaliable
Aerrane
side effects and Toxicity
LC50=15300 ppm/3 hrs (inhalation by rat)
Aerrane
Patient Information
Isoflurane, as well as other general anesthetics, may cause a slight decrease in intellectual function for 2 or 3
days following anesthesia. As with other anesthetics, small changes in moods and symptoms may persist for up to 6
days after administration.
Aerrane
Organisms Affected
Humans and other mammals