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Infliximab Brand names, Infliximab Analogs

Infliximab Brand Names Mixture

  • No information avaliable

Infliximab Chemical_Formula


Infliximab RX_link

Infliximab fda sheet

Infliximab msds (material safety sheet)

Infliximab Synthesis Reference

U.S. patent 6,015,557, Nagahira K, Fukuda Y, Oyama Y, Kurihara T, Nasu T, Kawashima H, Noguchi C, Oikawa S, Nakanishi T. Humanization of a mouse neutralizing monoclonal antibody against tumor necrosis factor-alpha (TNF-alpha).

Infliximab Molecular Weight


Infliximab Melting Point

61 oC (FAB fragment), 71 oC (whole mAb) - Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).

Infliximab H2O Solubility

No information avaliable

Infliximab State


Infliximab LogP


Infliximab Dosage Forms

Powder for solution; Solution (IV infusion)

Infliximab Indication

For treatment of Crohn's disease, psoriasis, rheumatoid arthitis and ankylosing spondylitis

Infliximab Pharmacology

Used in the treatment of auto-immune disorders such as Crohn's disease and rheumatoid arthritis. Infliximab binds to tumor necrosis factor alpha (TNFa) and inhibits binding of TNFa with its receptors. This reduces production of pro-inflammatory cytokines such as interleukins (IL) 1 and 6. This also limits leukocyte migration and expression of adhesion molecules by endothelial cells and leukocytes. Infliximab also limits the activation of neutrophil and eosinophil functional activity, reduces production of tissue degrading enzymes produced by synoviocytes and/or chondrocytes. Infliximab decreases synovitis and joint erosions in collagen-induced arthritis and allows eroded joints to heal.

Infliximab Absorption

No information avaliable

Infliximab side effects and Toxicity

No information avaliable

Infliximab Patient Information


Infliximab Organisms Affected

Humans and other mammals