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Remicade (Centocor Inc) Brand names, Remicade (Centocor Inc) Analogs

Remicade (Centocor Inc) Brand Names Mixture

  • No information avaliable

Remicade (Centocor Inc) Chemical_Formula


Remicade (Centocor Inc) RX_link

Remicade (Centocor Inc) fda sheet

Remicade (Centocor Inc) msds (material safety sheet)

Remicade (Centocor Inc) Synthesis Reference

U.S. patent 6,015,557, Nagahira K, Fukuda Y, Oyama Y, Kurihara T, Nasu T, Kawashima H, Noguchi C, Oikawa S, Nakanishi T. Humanization of a mouse neutralizing monoclonal antibody against tumor necrosis factor-alpha (TNF-alpha).

Remicade (Centocor Inc) Molecular Weight


Remicade (Centocor Inc) Melting Point

61 oC (FAB fragment), 71 oC (whole mAb) - Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).

Remicade (Centocor Inc) H2O Solubility

No information avaliable

Remicade (Centocor Inc) State


Remicade (Centocor Inc) LogP


Remicade (Centocor Inc) Dosage Forms

Powder for solution; Solution (IV infusion)

Remicade (Centocor Inc) Indication

For treatment of Crohn's disease, psoriasis, rheumatoid arthitis and ankylosing spondylitis

Remicade (Centocor Inc) Pharmacology

Used in the treatment of auto-immune disorders such as Crohn's disease and rheumatoid arthritis. Infliximab binds to tumor necrosis factor alpha (TNFa) and inhibits binding of TNFa with its receptors. This reduces production of pro-inflammatory cytokines such as interleukins (IL) 1 and 6. This also limits leukocyte migration and expression of adhesion molecules by endothelial cells and leukocytes. Infliximab also limits the activation of neutrophil and eosinophil functional activity, reduces production of tissue degrading enzymes produced by synoviocytes and/or chondrocytes. Infliximab decreases synovitis and joint erosions in collagen-induced arthritis and allows eroded joints to heal.

Remicade (Centocor Inc) Absorption

No information avaliable

Remicade (Centocor Inc) side effects and Toxicity

No information avaliable

Remicade (Centocor Inc) Patient Information


Remicade (Centocor Inc) Organisms Affected

Humans and other mammals