Hydrogenated Ergot Alkaloids
Brand names,
Hydrogenated Ergot Alkaloids
Analogs
Hydrogenated Ergot Alkaloids
Brand Names Mixture
Hydrogenated Ergot Alkaloids
Chemical_Formula
C33H45N5O5
Hydrogenated Ergot Alkaloids
RX_link
No information avaliable
Hydrogenated Ergot Alkaloids
fda sheet
Hydrogenated Ergot Alkaloids
msds (material safety sheet)
Hydrogenated Ergot Alkaloids
Synthesis Reference
No information avaliable
Hydrogenated Ergot Alkaloids
Molecular Weight
591.741 g/mol
Hydrogenated Ergot Alkaloids
Melting Point
No information avaliable
Hydrogenated Ergot Alkaloids
H2O Solubility
No information avaliable
Hydrogenated Ergot Alkaloids
State
Solid
Hydrogenated Ergot Alkaloids
LogP
2.615
Hydrogenated Ergot Alkaloids
Dosage Forms
Capsule; Liquid; Powder; Powder for solution; Solution; Syrup; Tablet
Hydrogenated Ergot Alkaloids
Indication
For use as an adjunct therapy for patients with dementia
Hydrogenated Ergot Alkaloids
Pharmacology
Ergoloid Mesylate may increase cerebral metabolism and blood flow. The role of this medication in the therapy of dementia is controversial. A recent controlled study in patients with Alzheimer's disease found that there was no advantage to the use of ergoloid mesylates compared to placebo, suggesting that ergoloid mesylates may lower scores on some cognitive and behavioral rating scales. Further study is needed to determine the risk-benefit profile of ergoloid mesylates in the treatment of dementia.
Hydrogenated Ergot Alkaloids
Absorption
Rapidly but incompletely (approximately 25%) absorbed from the gastrointestinal tract. Approximately 50% of the absorbed dose is eliminated by first-pass metabolism.
Hydrogenated Ergot Alkaloids
side effects and Toxicity
Symptoms of overdose include dyspnea, hypotension or hypertension, rapid weak pulse, delirium, nausea, vomiting, and bradycardia.
Hydrogenated Ergot Alkaloids
Patient Information
No information avaliable
Hydrogenated Ergot Alkaloids
Organisms Affected
Humans and other mammals