Herceptin (Genentech)
Herceptin (Genentech) Brand names, Herceptin (Genentech) Analogs
Herceptin (Genentech) Brand Names Mixture
- Filaribits Plus 180/136mg Chewable Tablet (Diethylcarbamazine citrate + Oxibendazole)
Herceptin (Genentech) Chemical_Formula
C6470H10012N1726O2013S42
Herceptin (Genentech) RX_link
http://www.rxlist.com/cgi/generic/trastuz.htm
Herceptin (Genentech) fda sheet
Herceptin (Genentech) msds (material safety sheet)
Herceptin (Genentech) Synthesis Reference
No information avaliable
Herceptin (Genentech) Molecular Weight
145531.5
Herceptin (Genentech) Melting Point
61 oC (FAB fragment), 71 oC (whole mAb)-Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).
Herceptin (Genentech) H2O Solubility
No information avaliable
Herceptin (Genentech) State
Liquid
Herceptin (Genentech) LogP
-0.415
Herceptin (Genentech) Dosage Forms
Solution (IV Infusion)
Herceptin (Genentech) Indication
For treatment of HER2-positive metatsatic breast cancer
Herceptin (Genentech) Pharmacology
Used in the treatment of HER2-positive breast cancer. HER2 protein overexpression is observed in 25%-30% of primary breast cancers.Trastuzumab has been shown, in both in vitro assays and in animals, to inhibit the proliferation of human tumorcells that overexpress HER2. It is a mediator of antibody dependent cellular cytotoxicity, in that the binding of the antibody to HER2 overexpressing cells leads to preferential cell death.
Herceptin (Genentech) Absorption
No information avaliable
Herceptin (Genentech) side effects and Toxicity
No information avaliable
Herceptin (Genentech) Patient Information
No information avaliable
Herceptin (Genentech) Organisms Affected
Humans and other mammals
