Anti HER2
Anti HER2 Brand names, Anti HER2 Analogs
Anti HER2 Brand Names Mixture
- Filaribits Plus 180/136mg Chewable Tablet (Diethylcarbamazine citrate + Oxibendazole)
Anti HER2 Chemical_Formula
C6470H10012N1726O2013S42
Anti HER2 RX_link
http://www.rxlist.com/cgi/generic/trastuz.htm
Anti HER2 fda sheet
Anti HER2 msds (material safety sheet)
Anti HER2 Synthesis Reference
No information avaliable
Anti HER2 Molecular Weight
145531.5
Anti HER2 Melting Point
61 oC (FAB fragment), 71 oC (whole mAb)-Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).
Anti HER2 H2O Solubility
No information avaliable
Anti HER2 State
Liquid
Anti HER2 LogP
-0.415
Anti HER2 Dosage Forms
Solution (IV Infusion)
Anti HER2 Indication
For treatment of HER2-positive metatsatic breast cancer
Anti HER2 Pharmacology
Used in the treatment of HER2-positive breast cancer. HER2 protein overexpression is observed in 25%-30% of primary breast cancers.Trastuzumab has been shown, in both in vitro assays and in animals, to inhibit the proliferation of human tumorcells that overexpress HER2. It is a mediator of antibody dependent cellular cytotoxicity, in that the binding of the antibody to HER2 overexpressing cells leads to preferential cell death.
Anti HER2 Absorption
No information avaliable
Anti HER2 side effects and Toxicity
No information avaliable
Anti HER2 Patient Information
No information avaliable
Anti HER2 Organisms Affected
Humans and other mammals
