Goserelin
Brand names,
Goserelin
Analogs
Goserelin
Brand Names Mixture
- Fluoracaine Oph Soln (Fluorescein Sodium + Proxymetacain Hcl)
- Fluorescein Sodium & Benoxinate Hydrochloride Ophtalmic Solution, Usp (Benoxinate Hydrochloride + Fluorescein Sodium)
- Fluress (Benoxinate Hydrochloride + Fluorescein Sodium)
- Fluress Liq Oph (Benoxinate Hydrochloride + Fluorescein Sodium)
Goserelin
Chemical_Formula
C59H84N18O14
Goserelin
RX_link
http://www.rxlist.com/cgi/generic/goserel.htm
Goserelin
fda sheet
Goserelin
msds (material safety sheet)
Goserelin
Synthesis Reference
Weber et al., U.S. Pat. 3,454,635 (1969)
Goserelin
Molecular Weight
1269.41 g/mol
Goserelin
Melting Point
No information avaliable
Goserelin
H2O Solubility
Soluble
Goserelin
State
Solid
Goserelin
LogP
-2.517
Goserelin
Dosage Forms
Supplied as a sterile and totally biodegradable d,l-lactic and glycolic acids copolymer (13.3-14.3 mg/dose) impregnated with goserelin acetate equivalent to 3.6 mg of goserelin in a disposable syringe device fitted with a 16-gauge hypodermic needle
Goserelin
Indication
Breast cancer; Prostate carcinoma; Endometriosis
Goserelin
Pharmacology
The pharmacokinetics of ZOLADEX have been determined in both male and female healthy volunteers and patients. In these studies, ZOLADEX was administered as a single 250µg (aqueous solution) dose and as a single or multiple 3.6 mg depot dose by subcutaneous route.
Goserelin
Absorption
Inactive orally, rapidly absorbed following subcutaneous administration
Goserelin
side effects and Toxicity
No experience of overdosage from clinical trials
Goserelin
Patient Information
BIOD00113.html
Goserelin
Organisms Affected
Humans and other mammals