Goserelin acetate
Brand names,
Goserelin acetate
Analogs
Goserelin acetate
Brand Names Mixture
- Fluoracaine Oph Soln (Fluorescein Sodium + Proxymetacain Hcl)
- Fluorescein Sodium & Benoxinate Hydrochloride Ophtalmic Solution, Usp (Benoxinate Hydrochloride + Fluorescein Sodium)
- Fluress (Benoxinate Hydrochloride + Fluorescein Sodium)
- Fluress Liq Oph (Benoxinate Hydrochloride + Fluorescein Sodium)
Goserelin acetate
Chemical_Formula
C59H84N18O14
Goserelin acetate
RX_link
http://www.rxlist.com/cgi/generic/goserel.htm
Goserelin acetate
fda sheet
Goserelin acetate
msds (material safety sheet)
Goserelin acetate
Synthesis Reference
Weber et al., U.S. Pat. 3,454,635 (1969)
Goserelin acetate
Molecular Weight
1269.41 g/mol
Goserelin acetate
Melting Point
No information avaliable
Goserelin acetate
H2O Solubility
Soluble
Goserelin acetate
State
Solid
Goserelin acetate
LogP
-2.517
Goserelin acetate
Dosage Forms
Supplied as a sterile and totally biodegradable d,l-lactic and glycolic acids copolymer (13.3-14.3 mg/dose) impregnated with goserelin acetate equivalent to 3.6 mg of goserelin in a disposable syringe device fitted with a 16-gauge hypodermic needle
Goserelin acetate
Indication
Breast cancer; Prostate carcinoma; Endometriosis
Goserelin acetate
Pharmacology
The pharmacokinetics of ZOLADEX have been determined in both male and female healthy volunteers and patients. In these studies, ZOLADEX was administered as a single 250µg (aqueous solution) dose and as a single or multiple 3.6 mg depot dose by subcutaneous route.
Goserelin acetate
Absorption
Inactive orally, rapidly absorbed following subcutaneous administration
Goserelin acetate
side effects and Toxicity
No experience of overdosage from clinical trials
Goserelin acetate
Patient Information
BIOD00113.html
Goserelin acetate
Organisms Affected
Humans and other mammals