Goserelin acetate (JAN/USP)
Brand names,
Goserelin acetate (JAN/USP)
Analogs
Goserelin acetate (JAN/USP)
Brand Names Mixture
- Fluoracaine Oph Soln (Fluorescein Sodium + Proxymetacain Hcl)
- Fluorescein Sodium & Benoxinate Hydrochloride Ophtalmic Solution, Usp (Benoxinate Hydrochloride + Fluorescein Sodium)
- Fluress (Benoxinate Hydrochloride + Fluorescein Sodium)
- Fluress Liq Oph (Benoxinate Hydrochloride + Fluorescein Sodium)
Goserelin acetate (JAN/USP)
Chemical_Formula
C59H84N18O14
Goserelin acetate (JAN/USP)
RX_link
http://www.rxlist.com/cgi/generic/goserel.htm
Goserelin acetate (JAN/USP)
fda sheet
Goserelin acetate (JAN/USP)
msds (material safety sheet)
Goserelin acetate (JAN/USP)
Synthesis Reference
Weber et al., U.S. Pat. 3,454,635 (1969)
Goserelin acetate (JAN/USP)
Molecular Weight
1269.41 g/mol
Goserelin acetate (JAN/USP)
Melting Point
No information avaliable
Goserelin acetate (JAN/USP)
H2O Solubility
Soluble
Goserelin acetate (JAN/USP)
State
Solid
Goserelin acetate (JAN/USP)
LogP
-2.517
Goserelin acetate (JAN/USP)
Dosage Forms
Supplied as a sterile and totally biodegradable d,l-lactic and glycolic acids copolymer (13.3-14.3 mg/dose) impregnated with goserelin acetate equivalent to 3.6 mg of goserelin in a disposable syringe device fitted with a 16-gauge hypodermic needle
Goserelin acetate (JAN/USP)
Indication
Breast cancer; Prostate carcinoma; Endometriosis
Goserelin acetate (JAN/USP)
Pharmacology
The pharmacokinetics of ZOLADEX have been determined in both male and female healthy volunteers and patients. In these studies, ZOLADEX was administered as a single 250µg (aqueous solution) dose and as a single or multiple 3.6 mg depot dose by subcutaneous route.
Goserelin acetate (JAN/USP)
Absorption
Inactive orally, rapidly absorbed following subcutaneous administration
Goserelin acetate (JAN/USP)
side effects and Toxicity
No experience of overdosage from clinical trials
Goserelin acetate (JAN/USP)
Patient Information
BIOD00113.html
Goserelin acetate (JAN/USP)
Organisms Affected
Humans and other mammals