Glycopyrrolate
Brand names,
Glycopyrrolate
Analogs
Glycopyrrolate
Brand Names Mixture
Glycopyrrolate
Chemical_Formula
C19H28NO3+
Glycopyrrolate
RX_link
http://www.rxlist.com/cgi/generic3/glycopyrrolate.htm
Glycopyrrolate
fda sheet
Glycopyrrolate
msds (material safety sheet)
Glycopyrrolate
Synthesis Reference
No information avaliable
Glycopyrrolate
Molecular Weight
318.431 g/mol
Glycopyrrolate
Melting Point
192.5 oC
Glycopyrrolate
H2O Solubility
No information avaliable
Glycopyrrolate
State
Solid
Glycopyrrolate
LogP
-0.99
Glycopyrrolate
Dosage Forms
Liquid; Tablet
Glycopyrrolate
Indication
For use as a preoperative antimuscarinic to reduce salivary, tracheobronchial, and pharyngeal secretions, to reduce the volume and free acidity of gastric secretions and to block cardiac vagal inhibitory reflexes during induction of anesthesia and intubation.
Glycopyrrolate
Pharmacology
Glycopyrrolate decreases acid secretion in the stomach. Hence it can be used for treating ulcers in the stomach and small intestine, in combination with other medications. In anesthesia, glycopyrrolate injection serves as a preoperative antimuscarinic operation that reduces salivary, tracheobronchial, and pharyngeal secretions, as well as decreases the acidity of gastric secretions blocks cardiac vagal inhibitory reflexes during intubation
Glycopyrrolate
Absorption
Rapidly absorbed (1-2 minutes) after intravenous injection
Glycopyrrolate
side effects and Toxicity
Side effects include dry mouth, difficult urinating, heachaches, diarrhea and constipation. The medication also induces drowsiness or blurred vision. LD50=709 mg/kg (rat, oral).
Glycopyrrolate
Patient Information
No information avaliable
Glycopyrrolate
Organisms Affected
Humans and other mammals