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Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
C19H28NO3+
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RX_link
http://www.rxlist.com/cgi/generic3/glycopyrrolate.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
318.431 g/mol
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Melting Point
192.5 oC
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H2O Solubility
No information avaliable
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State
Solid
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LogP
-0.99
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Dosage Forms
Liquid; Tablet
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Indication
For use as a preoperative antimuscarinic to reduce salivary, tracheobronchial, and pharyngeal secretions, to reduce the volume and free acidity of gastric secretions and to block cardiac vagal inhibitory reflexes during induction of anesthesia and intubation.
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Pharmacology
Glycopyrrolate decreases acid secretion in the stomach. Hence it can be used for treating ulcers in the stomach and small intestine, in combination with other medications. In anesthesia, glycopyrrolate injection serves as a preoperative antimuscarinic operation that reduces salivary, tracheobronchial, and pharyngeal secretions, as well as decreases the acidity of gastric secretions blocks cardiac vagal inhibitory reflexes during intubation
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Absorption
Rapidly absorbed (1-2 minutes) after intravenous injection
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side effects and Toxicity
Side effects include dry mouth, difficult urinating, heachaches, diarrhea and constipation. The medication also induces drowsiness or blurred vision. LD50=709 mg/kg (rat, oral).
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Patient Information
No information avaliable
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Organisms Affected
Humans and other mammals