Gliclazide
Brand names,
Gliclazide
Analogs
Gliclazide
Brand Names Mixture
Gliclazide
Chemical_Formula
C15H21N3O3S
Gliclazide
RX_link
No information avaliable
Gliclazide
fda sheet
Gliclazide
msds (material safety sheet)
Gliclazide
Synthesis Reference
No information avaliable
Gliclazide
Molecular Weight
323.412 g/mol
Gliclazide
Melting Point
181 oC
Gliclazide
H2O Solubility
No information avaliable
Gliclazide
State
Solid
Gliclazide
LogP
2.418
Gliclazide
Dosage Forms
Tablet
Gliclazide
Indication
For the treatment of Diabetes mellitus
Gliclazide
Pharmacology
Gliclazide is a second generation sulphonylurea which acts as a hypoglycemic agent. It stimulates beta cells of the islet of Langerhans in the pancreas to release insulin. It also enhances peripheral insulin sensitivity. Overall it potentiates insulin release and improves insulin dynamics.
Gliclazide
Absorption
Rapidly and well absorbed but may have wide inter- and intra-individual variability.
Gliclazide
side effects and Toxicity
LD50=3000 mg/kg (orally in mice)
Gliclazide
Patient Information
No information avaliable
Gliclazide
Organisms Affected
Humans and other mammals