Gliclazidum [INN-Latin]
Brand names,
Gliclazidum [INN-Latin]
Analogs
Gliclazidum [INN-Latin]
Brand Names Mixture
Gliclazidum [INN-Latin]
Chemical_Formula
C15H21N3O3S
Gliclazidum [INN-Latin]
RX_link
No information avaliable
Gliclazidum [INN-Latin]
fda sheet
Gliclazidum [INN-Latin]
msds (material safety sheet)
Gliclazidum [INN-Latin]
Synthesis Reference
No information avaliable
Gliclazidum [INN-Latin]
Molecular Weight
323.412 g/mol
Gliclazidum [INN-Latin]
Melting Point
181 oC
Gliclazidum [INN-Latin]
H2O Solubility
No information avaliable
Gliclazidum [INN-Latin]
State
Solid
Gliclazidum [INN-Latin]
LogP
2.418
Gliclazidum [INN-Latin]
Dosage Forms
Tablet
Gliclazidum [INN-Latin]
Indication
For the treatment of Diabetes mellitus
Gliclazidum [INN-Latin]
Pharmacology
Gliclazide is a second generation sulphonylurea which acts as a hypoglycemic agent. It stimulates beta cells of the islet of Langerhans in the pancreas to release insulin. It also enhances peripheral insulin sensitivity. Overall it potentiates insulin release and improves insulin dynamics.
Gliclazidum [INN-Latin]
Absorption
Rapidly and well absorbed but may have wide inter- and intra-individual variability.
Gliclazidum [INN-Latin]
side effects and Toxicity
LD50=3000 mg/kg (orally in mice)
Gliclazidum [INN-Latin]
Patient Information
No information avaliable
Gliclazidum [INN-Latin]
Organisms Affected
Humans and other mammals