Gliclazida [INN-Spanish]
Brand names,
Gliclazida [INN-Spanish]
Analogs
Gliclazida [INN-Spanish]
Brand Names Mixture
Gliclazida [INN-Spanish]
Chemical_Formula
C15H21N3O3S
Gliclazida [INN-Spanish]
RX_link
No information avaliable
Gliclazida [INN-Spanish]
fda sheet
Gliclazida [INN-Spanish]
msds (material safety sheet)
Gliclazida [INN-Spanish]
Synthesis Reference
No information avaliable
Gliclazida [INN-Spanish]
Molecular Weight
323.412 g/mol
Gliclazida [INN-Spanish]
Melting Point
181 oC
Gliclazida [INN-Spanish]
H2O Solubility
No information avaliable
Gliclazida [INN-Spanish]
State
Solid
Gliclazida [INN-Spanish]
LogP
2.418
Gliclazida [INN-Spanish]
Dosage Forms
Tablet
Gliclazida [INN-Spanish]
Indication
For the treatment of Diabetes mellitus
Gliclazida [INN-Spanish]
Pharmacology
Gliclazide is a second generation sulphonylurea which acts as a hypoglycemic agent. It stimulates beta cells of the islet of Langerhans in the pancreas to release insulin. It also enhances peripheral insulin sensitivity. Overall it potentiates insulin release and improves insulin dynamics.
Gliclazida [INN-Spanish]
Absorption
Rapidly and well absorbed but may have wide inter- and intra-individual variability.
Gliclazida [INN-Spanish]
side effects and Toxicity
LD50=3000 mg/kg (orally in mice)
Gliclazida [INN-Spanish]
Patient Information
No information avaliable
Gliclazida [INN-Spanish]
Organisms Affected
Humans and other mammals