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Gefitinib Brand names, Gefitinib Analogs

Gefitinib Brand Names Mixture

  • No information avaliable

Gefitinib Chemical_Formula

C22H24ClFN4O3

Gefitinib RX_link

http://www.rxlist.com/cgi/generic3/iressa.htm

Gefitinib fda sheet

Gefitinib FDA

Gefitinib msds (material safety sheet)

Gefitinib MSDS

Gefitinib Synthesis Reference

No information avaliable

Gefitinib Molecular Weight

446.902 g/mol

Gefitinib Melting Point

No information avaliable

Gefitinib H2O Solubility

Sparingly soluble (<pH4)

Gefitinib State

Solid

Gefitinib LogP

3.46

Gefitinib Dosage Forms

Tablet

Gefitinib Indication

For the continued treatment of patients with locally advanced or metastatic non-small cell lung cancer after failure of either platinum-based or docetaxel chemotherapies.

Gefitinib Pharmacology

Gefitinib inhibits the intracellular phosphorylation of numerous tyrosine kinases associated with transmembrane cell surface receptors, including the tyrosine kinases associated with the epidermal growth factor receptor (EGFR-TK). EGFR is expressed on the cell surface of many normal cells and cancer cells.

Gefitinib Absorption

Absorbed slowly after oral administration with mean bioavailability of 60%.

Gefitinib side effects and Toxicity

No information avaliable

Gefitinib Patient Information

Gefitinib Organisms Affected

Humans and other mammals