Iressa
Iressa Brand names, Iressa Analogs
Iressa Brand Names Mixture
- No information avaliable
Iressa Chemical_Formula
C22H24ClFN4O3
Iressa RX_link
http://www.rxlist.com/cgi/generic3/iressa.htm
Iressa fda sheet
Iressa msds (material safety sheet)
Iressa Synthesis Reference
No information avaliable
Iressa Molecular Weight
446.902 g/mol
Iressa Melting Point
No information avaliable
Iressa H2O Solubility
Sparingly soluble (<pH4)
Iressa State
Solid
Iressa LogP
3.46
Iressa Dosage Forms
Tablet
Iressa Indication
For the continued treatment of patients with locally advanced or metastatic non-small cell lung cancer after failure of either platinum-based or docetaxel chemotherapies.
Iressa Pharmacology
Gefitinib inhibits the intracellular phosphorylation of numerous tyrosine kinases associated with transmembrane cell surface receptors, including the tyrosine kinases associated with the epidermal growth factor receptor (EGFR-TK). EGFR is expressed on the cell surface of many normal cells and cancer cells.
Iressa Absorption
Absorbed slowly after oral administration with mean bioavailability of 60%.
Iressa side effects and Toxicity
No information avaliable
Iressa Patient Information
Iressa Organisms Affected
Humans and other mammals
