Gatifloxacin
Gatifloxacin Brand names, Gatifloxacin Analogs
Gatifloxacin Brand Names Mixture
- GyneCure Vaginal Ointment Tandempak 6.5% (Tioconazole + other)
- GyneCure Vaginal Ovules Tandempak (Tioconazole + other)
Gatifloxacin Chemical_Formula
C19H22FN3O4
Gatifloxacin RX_link
http://www.rxlist.com/cgi/generic3/gatifloxacin.htm
Gatifloxacin fda sheet
Gatifloxacin msds (material safety sheet)
Gatifloxacin Synthesis Reference
No information avaliable
Gatifloxacin Molecular Weight
375.394 g/mol
Gatifloxacin Melting Point
182-185 oC
Gatifloxacin H2O Solubility
60 mg/mL (at pH 4)
Gatifloxacin State
Solid
Gatifloxacin LogP
1.801
Gatifloxacin Dosage Forms
Liquid; Solution; Tablet
Gatifloxacin Indication
For the treatment of bronchitis, sinusitis, community-acquired pneumonia, and skin infections (abscesses, wounds) caused by S. pneumoniae, H. influenzae, S. aureus, M. pneumoniae, C. pneumoniae, L. pneumophila, S. pyogenes
Gatifloxacin Pharmacology
Gatifloxacin is a synthetic broad-spectrum 8-methoxyfluoroquinolone antibacterial agent for oral or intravenous administration. is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase, which allows the untwisting required to replicate one DNA double helix into two. Notably the drug has 100 times higher affinity for bacterial DNA gyrase than for mammalian. Gatifloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. It should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.
Gatifloxacin Absorption
Well absorbed from the gastrointestinal tract after oral administration with absolute bioavailability of gatifloxacin is 96%
Gatifloxacin side effects and Toxicity
No information avaliable
Gatifloxacin Patient Information
No information avaliable
Gatifloxacin Organisms Affected
Enteric bacteria and other eubacteria
