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Gatifloxacin Brand names, Gatifloxacin Analogs

Gatifloxacin Brand Names Mixture

  • GyneCure Vaginal Ointment Tandempak 6.5% (Tioconazole + other)
  • GyneCure Vaginal Ovules Tandempak (Tioconazole + other)

Gatifloxacin Chemical_Formula

C19H22FN3O4

Gatifloxacin RX_link

http://www.rxlist.com/cgi/generic3/gatifloxacin.htm

Gatifloxacin fda sheet

Gatifloxacin FDA

Gatifloxacin msds (material safety sheet)

Gatifloxacin MSDS

Gatifloxacin Synthesis Reference

No information avaliable

Gatifloxacin Molecular Weight

375.394 g/mol

Gatifloxacin Melting Point

182-185 oC

Gatifloxacin H2O Solubility

60 mg/mL (at pH 4)

Gatifloxacin State

Solid

Gatifloxacin LogP

1.801

Gatifloxacin Dosage Forms

Liquid; Solution; Tablet

Gatifloxacin Indication

For the treatment of bronchitis, sinusitis, community-acquired pneumonia, and skin infections (abscesses, wounds) caused by S. pneumoniae, H. influenzae, S. aureus, M. pneumoniae, C. pneumoniae, L. pneumophila, S. pyogenes

Gatifloxacin Pharmacology

Gatifloxacin is a synthetic broad-spectrum 8-methoxyfluoroquinolone antibacterial agent for oral or intravenous administration. is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase, which allows the untwisting required to replicate one DNA double helix into two. Notably the drug has 100 times higher affinity for bacterial DNA gyrase than for mammalian. Gatifloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. It should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.

Gatifloxacin Absorption

Well absorbed from the gastrointestinal tract after oral administration with absolute bioavailability of gatifloxacin is 96%

Gatifloxacin side effects and Toxicity

No information avaliable

Gatifloxacin Patient Information

No information avaliable

Gatifloxacin Organisms Affected

Enteric bacteria and other eubacteria