Flumazenil
Brand names,
Flumazenil
Analogs
Flumazenil
Brand Names Mixture
Flumazenil
Chemical_Formula
C15H14FN3O3
Flumazenil
RX_link
http://www.rxlist.com/cgi/generic3/flumazenil.htm
Flumazenil
fda sheet
Flumazenil
msds (material safety sheet)
Flumazenil
Synthesis Reference
No information avaliable
Flumazenil
Molecular Weight
303.288 g/mol
Flumazenil
Melting Point
201-203 oC
Flumazenil
H2O Solubility
128 mg/L
Flumazenil
State
Solid
Flumazenil
LogP
1.468
Flumazenil
Dosage Forms
Solution for injection (0.1 mg/mL)
Flumazenil
Indication
For the complete or partial reversal of the sedative effects of benzodiazepines in cases where general anesthesia has been induced and/or maintained with benzodiazepines, where sedation has been produced with benzodiazepines for diagnostic and therapeutic procedures, and for the management of benzodiazepine overdose.
Flumazenil
Pharmacology
Flumazenil does not antagonize the central nervous system effects of drugs affecting GABA-ergic neurons by means other than the benzodiazepine receptor (including ethanol, barbiturates, or general anesthetics) and does not reverse the effects of opioids.
Flumazenil
Absorption
No information avaliable
Flumazenil
side effects and Toxicity
In clinical studies, most adverse reactions to flumazenil were an extension of the pharmacologic effects of the drug in reversing benzodiazepine effects.
Flumazenil
Patient Information
Flumazenil
Organisms Affected
Humans and other mammals