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Flecainide Brand names, Flecainide Analogs

Flecainide Brand Names Mixture

  • No information avaliable

Flecainide Chemical_Formula

C17H20F6N2O3

Flecainide RX_link

http://www.rxlist.com/cgi/generic2/flecainide.htm

Flecainide fda sheet

Flecainide msds (material safety sheet)

http://www.siri.org/msds/files/bxx/bxxmq.html

Flecainide Synthesis Reference

No information avaliable

Flecainide Molecular Weight

414.343 g/mol

Flecainide Melting Point

No information avaliable

Flecainide H2O Solubility

48.4 mg/mL at 37oC (acetate form)

Flecainide State

Solid

Flecainide LogP

4.06

Flecainide Dosage Forms

Tablet (50, 100, 150 mg)

Flecainide Indication

For the prevention of paroxysmal supraventricular tachycardias (PSVT), including atrioventricular nodal reentrant tachycardia, atrioventricular reentrant tachycardia and other supraventricular tachycardias of unspecified mechanism associated with disablin.

Flecainide Pharmacology

Flecainide has local anesthetic activity and belongs to the membrane stabilizing (Class 1) group of antiarrhythmic agents; it has electrophysiologic effects characteristic of the IC class of antiarrhythmics.

Flecainide Absorption

Nearly complete following oral administration.

Flecainide side effects and Toxicity

Oral LD50 is 50-498 mg/kg in rat. Symptoms of overdose include nausea and vomiting, convulsions, hypotension, bradycardia, syncope, extreme widening of the QRS complex, widening of the QT interval, widening of the PR interval, ventricular tachycardia, AV nodal block, asystole, bundle branch block, cardiac failure, and cardiac arrest.

Flecainide Patient Information

No information avaliable

Flecainide Organisms Affected

Humans and other mammals