Flecainide
Flecainide Brand names, Flecainide Analogs
Flecainide Brand Names Mixture
- No information avaliable
Flecainide Chemical_Formula
C17H20F6N2O3
Flecainide RX_link
http://www.rxlist.com/cgi/generic2/flecainide.htm
Flecainide fda sheet
Flecainide msds (material safety sheet)
Flecainide Synthesis Reference
No information avaliable
Flecainide Molecular Weight
414.343 g/mol
Flecainide Melting Point
No information avaliable
Flecainide H2O Solubility
48.4 mg/mL at 37oC (acetate form)
Flecainide State
Solid
Flecainide LogP
4.06
Flecainide Dosage Forms
Tablet (50, 100, 150 mg)
Flecainide Indication
For the prevention of paroxysmal supraventricular tachycardias (PSVT), including atrioventricular nodal reentrant tachycardia, atrioventricular reentrant tachycardia and other supraventricular tachycardias of unspecified mechanism associated with disablin.
Flecainide Pharmacology
Flecainide has local anesthetic activity and belongs to the membrane stabilizing (Class 1) group of antiarrhythmic agents; it has electrophysiologic effects characteristic of the IC class of antiarrhythmics.
Flecainide Absorption
Nearly complete following oral administration.
Flecainide side effects and Toxicity
Oral LD50 is 50-498 mg/kg in rat. Symptoms of overdose include nausea and vomiting, convulsions, hypotension, bradycardia, syncope, extreme widening of the QRS complex, widening of the QT interval, widening of the PR interval, ventricular tachycardia, AV nodal block, asystole, bundle branch block, cardiac failure, and cardiac arrest.
Flecainide Patient Information
No information avaliable
Flecainide Organisms Affected
Humans and other mammals
