Flecaine
Flecaine Brand names, Flecaine Analogs
Flecaine Brand Names Mixture
- No information avaliable
Flecaine Chemical_Formula
C17H20F6N2O3
Flecaine RX_link
http://www.rxlist.com/cgi/generic2/flecainide.htm
Flecaine fda sheet
Flecaine msds (material safety sheet)
Flecaine Synthesis Reference
No information avaliable
Flecaine Molecular Weight
414.343 g/mol
Flecaine Melting Point
No information avaliable
Flecaine H2O Solubility
48.4 mg/mL at 37oC (acetate form)
Flecaine State
Solid
Flecaine LogP
4.06
Flecaine Dosage Forms
Tablet (50, 100, 150 mg)
Flecaine Indication
For the prevention of paroxysmal supraventricular tachycardias (PSVT), including atrioventricular nodal reentrant tachycardia, atrioventricular reentrant tachycardia and other supraventricular tachycardias of unspecified mechanism associated with disablin.
Flecaine Pharmacology
Flecainide has local anesthetic activity and belongs to the membrane stabilizing (Class 1) group of antiarrhythmic agents; it has electrophysiologic effects characteristic of the IC class of antiarrhythmics.
Flecaine Absorption
Nearly complete following oral administration.
Flecaine side effects and Toxicity
Oral LD50 is 50-498 mg/kg in rat. Symptoms of overdose include nausea and vomiting, convulsions, hypotension, bradycardia, syncope, extreme widening of the QRS complex, widening of the QT interval, widening of the PR interval, ventricular tachycardia, AV nodal block, asystole, bundle branch block, cardiac failure, and cardiac arrest.
Flecaine Patient Information
No information avaliable
Flecaine Organisms Affected
Humans and other mammals
