Flecainide acetate
Brand names,
Flecainide acetate
Analogs
Flecainide acetate
Brand Names Mixture
Flecainide acetate
Chemical_Formula
C17H20F6N2O3
Flecainide acetate
RX_link
http://www.rxlist.com/cgi/generic2/flecainide.htm
Flecainide acetate
fda sheet
Flecainide acetate
msds (material safety sheet)
Flecainide acetate
Synthesis Reference
No information avaliable
Flecainide acetate
Molecular Weight
414.343 g/mol
Flecainide acetate
Melting Point
No information avaliable
Flecainide acetate
H2O Solubility
48.4 mg/mL at 37oC (acetate form)
Flecainide acetate
State
Solid
Flecainide acetate
LogP
4.06
Flecainide acetate
Dosage Forms
Tablet (50, 100, 150 mg)
Flecainide acetate
Indication
For the prevention of paroxysmal supraventricular tachycardias (PSVT), including atrioventricular nodal reentrant tachycardia, atrioventricular reentrant tachycardia and other supraventricular tachycardias of unspecified mechanism associated with disablin.
Flecainide acetate
Pharmacology
Flecainide has local anesthetic activity and belongs to the membrane stabilizing (Class 1) group of antiarrhythmic agents; it has electrophysiologic effects characteristic of the IC class of antiarrhythmics.
Flecainide acetate
Absorption
Nearly complete following oral administration.
Flecainide acetate
side effects and Toxicity
Oral LD50 is 50-498 mg/kg in rat. Symptoms of overdose include nausea and vomiting, convulsions, hypotension, bradycardia, syncope, extreme widening of the QRS complex, widening of the QT interval, widening of the PR interval, ventricular tachycardia, AV nodal block, asystole, bundle branch block, cardiac failure, and cardiac arrest.
Flecainide acetate
Patient Information
No information avaliable
Flecainide acetate
Organisms Affected
Humans and other mammals