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Felbamate en es it fr

Felbamate Brand names, Felbamate Analogs

Felbamate Brand Names Mixture

  • No information avaliable

Felbamate Chemical_Formula

C11H14N2O4

Felbamate RX_link

http://www.rxlist.com/cgi/generic3/felbamate.htm

Felbamate fda sheet

Felbamate msds (material safety sheet)

Felbamate MSDS

Felbamate Synthesis Reference

No information avaliable

Felbamate Molecular Weight

238.24 g/mol

Felbamate Melting Point

151.5 oC

Felbamate H2O Solubility

Slightly soluble in water

Felbamate State

Solid

Felbamate LogP

0.76

Felbamate Dosage Forms

Tablet; Suspension

Felbamate Indication

For use only in those patients who respond inadequately to alternative treatments and whose epilepsy is so severe that a substantial risk of aplastic anemia and/or liver failure is deemed acceptable in light of the benefits conferred by its use.

Felbamate Pharmacology

Felbamate is an antiepileptic indicated as monotherapy or as an adjunct to other anticonvulsants for the treatment of partial seizures resulting from epilepsy. Receptor-binding studies in vitro indicate that felbamate has weak inhibitory effects on GABA-receptor binding, benzodiazepine receptor binding, and is devoid of activity at the MK-801 receptor binding site of the NMDA receptor-ionophore complex. However, felbamate does interact as an antagonist at the strychnine-insensitive glycine recognition site of the NMDA receptor-ionophore complex.

Felbamate Absorption

>90%

Felbamate side effects and Toxicity

LD50=5000 mg/kg (Orally in rats)

Felbamate Patient Information

Patient Information:

Felmabate can cause severe blood abnormality, hepatic failure and other fatal
conditions. Talk about the risks and side effects with your doctor before taking it.

Do not stop the medication without consulting your doctor. Finish the medication
even if you feel better.

Felbamate Organisms Affected

Humans and other mammals